What Does It Do And Ought to You Begin Taking It?

What Is Glutamine | Glutamine Benefits | Popular Products | FAQ | Supplements With Glutamine | Side Effects And Warnings | Disclaimer

Glutamine is likely one of the important amino acids that our physique must operate correctly. It’s a non-essential amino acid, that means our physique can produce it by itself. Nevertheless, sure situations, akin to intense train, sickness, or damage, could enhance the demand for glutamine. On this weblog submit, we are going to take a more in-depth take a look at what glutamine is, why it can be crucial, and the way it can profit our our bodies.

Section Divider: What Is Glutamine

Glutamine is a kind of amino acid that’s generally present in our our bodies. It’s categorized as a non-essential amino acid, that means our physique can produce it independently. It’s made up of the amino acids glutamic acid and ammonia, which mix to kind L-glutamine, the most typical type of glutamine present in our physique.

Glutamine is an important constructing block of proteins, that are important for the expansion and restore of tissues, together with muscle tissues. Additionally it is concerned in a number of metabolic processes, akin to glucose manufacturing within the liver and the regulation of acid-base stability within the physique. Though our physique can produce glutamine, sure situations, akin to intense train, sickness, or damage, can enhance the demand for glutamine. Throughout these situations, our physique could also be unable to provide sufficient glutamine to fulfill the elevated demand, resulting in a deficiency. In such instances, glutamine supplementation could also be obligatory to keep up optimum well being. (1,2)

However, it’s additionally naturally present in meals like: (3)

  • Beef
  • Tofu
  • Eggs
  • Skim milk
  • White Rice
  • Corn

Section Divider: Glutamine Benefits

L Glutamine Advantages:

On this part, we’ll be going over what glutamine does and the advantages of supplementing with it!

  • Immune System
  • Intestine And Digestive Well being
  • Muscle Restoration
  • Coronary heart Well being

Glutamine And Your Immune System:

Glutamine performs a big position in selling your immunity by fueling immune cells like white blood cells. So naturally, when your physique is in a state of illness or damage, your want for glutamine can enhance. Nevertheless, if the availability of glutamine is decrease than your physique’s wants, your physique could break down protein shops, akin to muscle. (3,4,5)


1. Anabolic, anticatabolic
2. Stimulates human progress hormone launch
3. Acts as an Antioxidant
4. Direct gasoline for quickly dividing cells
5. Immune stimulant
6. Shuttle for ammonia
7. Synthesis for purine and pyrimidines

These properties of glutamine could help with lowering the chance of wound an infection and will enhance the therapeutic of wounds. Although it might not dramatically influence the wound by itself. (3)

Glutamine And Intestine Well being:

Your intestinal well being is expounded to your immune system, aka intestine and digestive well being. That is in all probability why you’re right here, so let’s begin by saying present analysis does assist the claims that glutamine may also help with intestine well being. (6) In case you didn’t know, there are trillions of excellent micro organism in your intestines that make up your intestine flora. As a supply of power for intestinal and immune cells, glutamine may also help keep a barrier between your intestine and the remainder of your physique. This helps defend towards leaky intestine and different pathogens that may result in sickness or irritation.  Present analysis additionally exhibits that glutamine supplementation not solely helps barrier upkeep but additionally can enhance operate. (7)

Moreover, analysis suggests supplementation could profit gastrointestinal issues like inflammatory bowel illness (IBD) and irritable bowel syndrome (IBS). Nevertheless, various research point out that these advantages could also be restricted to remission occasions, not throughout flares. (8,9)

Does It Assist With Bloating?

As l-glutamine may also help with situations related to IBD and IBS, it might additionally assist scale back signs like: (8,9,10)

  • Bloating†
  • Constipation†
  • Cramping†
  • and so on.

Nevertheless, extra analysis is critical to indicate if supplementing with glutamine can profit people with out gastrointestinal issues.

 Muscle Restoration:

Certainly one of glutamine’s most well-known advantages is as an ergogenic support. Whereas analysis on this profit can contradict, there may be analysis that helps glutamine’s capacity to stop muscle catabolism (breakdown) and scale back muscle soreness. (11,12) Nevertheless, analysis doesn’t at present point out this amino acid can straight promote power or muscle progress. And several other research counsel that it essentially boosts efficiency, regardless of lowering fatigue. (13)

Coronary heart Well being:

New research are rising which counsel l glutamine could also be helpful for cardiovascular well being and illness. As a result of its potent antioxidant and anti inflammatory properties, glutamine could assist scale back threat elements for cardiovascular ailments like hypertension. (14)

Section Divider: Popular Products

Fashionable Merchandise:

Right here we’ll record some standard l-glutamine merchandise and methods to take them!

Optimum Nutrition Glutamine

How To Take Optimum Nutrition Glutamine:

Caps: The manufacturer recommends taking 1-2 capsules 30-45 minutes before workouts and/or immediately after workouts.

Powder: The manufacturer recommends mixing one (1) rounded teaspoon (5g) with 8oz water or your favorite beverage.

Customer Review By Andrew: “This is a great product. I have been taking it for years and feel its helped me maintain my results throughout fitness and health journey.”

AllMax Nutrition Glutamine


How To Take AllMax Nutrition Glutamine:

The manufacturer recommends mixing one (1) rounded teaspoon (5g) in water or juice once daily. For training sessions and athletic events, take approximately 30 minutes prior to training and immediately after training to help prevent muscle tissue breakdown and aid muscle recovery. At times when you are not training, mix 1 rounded teaspoon (5g) in water or juice approximately 45-60 minutes prior to meals.

Customer Review By Gilmar: “First time a bought this Allmax Glutamine to help on my recovery. Very happy with the results!”

NOW Foods L-Glutamine

How To Take NOW Foods L-Glutamine (Veg Capsules):

The manufacturer recommends taking one (1) capsule 1 to 3 times daily, preferably between meals. Store in a cool, dry place after opening.

Customer Review By David: “I have more energy, as well as my relief from acid reflux. My sweet craving has also diminished. I’ve been taking L Glutamine for 5 weeks. I will be placing another order.”

Nutrex Glutamine Drive

How To Take Nutrex Glutamine Drive:

The manufacturer recommends mixing one (1) scoop with 6-8oz of water or any beverage of your choice. They also suggest taking two (2) servings daily; one in the morning upon rising and one before going to bed. On training days, you may want to take an extra serving following your workout.

Customer Review Gary: “Easy to mix, and great for recovery. A must for any serious lifter, or athlete.”

Section Divider: Glutamine FAQs

Glutamine FAQs:

In this section, we’re tackling some of your most frequently asked questions about l glutamine!

Glutamine VS Glutamate

Both glutamine and glutamate belong to the family of amino acids, the “glutamate family.” Where l glutamate is the most abundant free amino acid in the brain, but it is also a non-essential amino acid. This amino acid is the major excitatory neurotransmitter of the central nervous system. Through the synthesis of l glutamine and Kreb’s cycle intermediates, glutamic acid in the brain is formed. Here, glutamate plays a role in many neuronal functions, like synaptic maintenance and plasticity. (15)

Glutamine VS Glutamate Structure

Glutamine For Temper?

It’s doable, as some research counsel, that a rise within the glutamine–glutamate ratio could enhance temper and cognition. Nevertheless, different research’ outcomes counsel that the buildup of glutamine within the blood and mind can negatively have an effect on mind operate. In the end, extra analysis is critical to know the connection between glutamine and cognition/temper. (16,17)

Can It Assist With Weight Loss?

A pilot analysis examine’s outcomes counsel that glutamine supplementation could enhance insulin sensitivity in sick sufferers and will improve glucose metabolism. Related outcomes had been present in a latest examine targeted on obese and overweight populations. These outcomes do counsel that glutamine supplementation could help with weight reduction. Nevertheless, extra analysis is critical to evaluate whether or not these outcomes are in step with various teams. (18,19,20)

Ought to You Stack It With Creatine?

Each creatine and glutamine could help with muscle restoration and promote efficiency. Nevertheless, the research on glutamine’s results on muscle progress and efficiency are usually not as clear as these with creatine. So whereas these dietary supplements is usually a nice stack for some people, others could not get to expertise all of the potential advantages. (21,22)

Section Divider: Supplements With Glutamine

Dietary supplements With Glutamine:

Relating to amino acids, you’ve gotten the lucky alternative to get them from quite a lot of sources. Likewise, glutamine may be supplemented by itself or with different blends. On this part, we’re going to dive into some standard intra and post-workout dietary supplements that characteristic glutamine. 

Formula 19 Supplement Facts

Our first post-workout supplement is Blackstone Lab’s Formula 19. Formula 19 features a recovery carbohydrate formula with four ingredients, including 9 grams of glutamine per serving.

R3 Carbohydrate Blend:

Current research studies support consuming carbohydrates post-workout as a way to replenish muscle glycogen stores. (23)


L-Leucine is our first ingredient aside of the branched-chain amino acids trio. This amino could contribute to protein synthesis and muscle restore. (24,25)

Magnesium Glycyl Glutamine:

Magnesium Glycyl-Glutamine may also help promote the restoration and anabolic advantages of glutamine with the improved metabolic processes from magnesium. (26)

How To Take Blackstone Labs System 19:

The producer recommends males combine two (2) scoops in 8-10 oz. of water and take them post-workout on coaching days. Whereas ladies combine one (1) scoop in 8-10 oz. of water and take it post-workout on coaching days.

Buyer Assessment By John: “Retains me powered up by means of my exercise, nice pumps and muscle fullness.”

alani nu bcaa Supplement FactsOur next featured product is Alani Nu BCAA. This formula features a simple 5-gram BCAA formula with only .5 grams of glutamine. Unfortunately, this is lower than most recommendations for glutamine, as it is often supplemented at doses between 5-30 grams. (28


Isoleucine is a part of the three branched-chain amino acids (BCAAs). It performs a job in muscle metabolism, together with constructing and repairing muscle. Isoleucine is a vital amino acid, so it’s worthwhile to eat it from meals or dietary supplements. The present suggestion of isoleucine for adults is round 13 mg every day. Nevertheless, for muscle progress, it’s common to see isoleucine in a BCAA complement dosed in a 2:1:1 ratio with leucine and valine. (29,24)


Valine is our final of the branched-chain amino acids and our final shared amino acid between the merchandise. And like the opposite two, valine helps stimulate muscle progress, restore, and power manufacturing. (24,30)

How To Take Alani Nu BCAA:

The producers suggest mixing one (1) scoop per 8-10oz of water. Shake nicely for one of the best consistency and taste. This product is finest consumed throughout train or in between meals.

Buyer Assessment By Michele: “Can’t do a exercise with out this! It’s a sport changer. Prevents me from being sore and I’ve a significantly better exercise! Completely adore it. And it’s scrumptious too!”

Xtend Supplement FactsNext, we have Scivation Xtend BCAA, one of our more popular BCAA supplements. This intra-workout supplement features 7 grams of BCAAs and 2.5 grams of glutamine. In addition to these ingredients, Xtend also features around 1.2 grams of electrolytes and 1 gram of citrulline malate.

Electrolyte Blend:

This blend of potassium and sodium can assist with maintaining hydration and promoting muscle repair. (31,32,33)

Citrulline Malate:

Citrulline Malate combines the nonessential amino acid L Citrulline and Malic Acid. This amino acid performs a job in enhancing train efficiency and widening your blood vessels, which can support in enhancing muscle progress. (34,35)

How To Take Scivation Xtend BCAA:

The producer recommends mixing two (2) scoops every day in 10-14 fl. oz. of water (modify for style desire) and shake nicely.

  • On coaching days: Combine one (1) scoop throughout train and one (1) scoop after train.
  • On non-training days: Combine two (2) scoops all through the day.

Buyer Assessment By Mathew: “Fruit Punch is our favourite, & it actually helps for exercises, simply can’t do with out it, however for some motive unable discover the 90 servings domestically, so was blissful to search out this retailer. It arrived shortly, which was nice since low on our present batch, so that is our go to provider going ahead.”

BCAA Optima Supplement FactsOur next BCAA matrix comes from NutraKey’s BCAA Optima. This formula features 7 grams of BCAAs like Xtend but with 100 mg more glutamine and 500 mg less of citrulline malate. However, unlike in Xtend, BCAA Optima also features Taurine in its electrolyte blend.


Taurine is an amino acid found commonly in the brain. It serves multiple purposes in the body including (36): 

  • Sustaining hydration and electrolytes
  • Regulates minerals akin to calcium
  • Helps the nervous system and eyes
  • Regulate immune system features

However, taurine additionally could enhance train efficiency research counsel that taurine could support in eradicating waste merchandise that result in fatigue and muscle burn. This interprets to it being efficient in selling endurance, growing alertness, and enhancing restoration. (37)

How To Take Nutrakey BCAA Optima:

The producers suggest mixing one (1) scoop with 8-12 oz. of water earlier than your exercise and one (1) scoop with 8-12 oz. of water an hour after your exercise. Nevertheless, it’s possible you’ll need to modify the servings based mostly in your way of life. The producers suggest casual-light exercise take one (1) scoop post-workout. Whereas customers with a extra moderate-weekly exercise degree could need to take one (1) scoop post-workout and one (1) scoop earlier than mattress. Athletes could need to take one (1) scoop with a meal and one (1) scoop earlier than and after a exercise.

Buyer Assessment By Robert: “These BCAA’s are nice! Style nice and will get the job finished. Extremely really helpful!”

BCAA Supreme Supplement FactsAnd the last intra-post workout supplement in our list is BCAA Supreme from USP Labs. This formula features a proprietary blend, so we wouldn’t be able to compare each of the ingredients directly. In addition to BCAAs, BCAA Supreme also features L-Alanine, Taurine, Glycine, L-Lysine HCl, and L-Alanyl-L-Glutamine (aka Sustamine™).


Alanine or beta alanine is a popular ingredient for pre workouts, which is because beta alanine can help aid performance. This amino acid can help buffer away lactic acid build-up, which is associated with the “burn” effect of training a muscle. For these benefits, you would need around 2-5 grams of beta alanine. (38)


Along with being an amino acid, the physique makes use of glycine to make glutathione (an antioxidant) which is a element of creatine and collagen. This ingredient could assist improve cognitive operate, decrease blood stress, and will assist management blood glucose. (39)

L-Lysine HCl:

Lysine is one other amino acid that may play a job in protein synthesis. It additionally helps hormone and enzyme manufacturing and different features.  (24,40)


Sustamine™ is a mixture of two amino acids, L-glutamine and L-alanine. This mixture has potential protecting, absorption-enhancing actions and even inhibits muscle protein catabolism (muscle breakdown). (41

How To Take USP Labs BCAA Supreme:

The producers suggest mixing one (1) serving (2 degree scoops) in 20 ounces of water and shaking vigorously for 30 seconds. Sip all through a exercise, athletic occasion, or any time further amino acids are wanted. As a result of excessive leucine content material, some preliminary foaming could happen, which ought to subside over a couple of minutes with mild shaking. Shake the container earlier than every use to disperse components that will have settled.

Buyer Assessment By Jacob: “Simply received it at this time. Rocket Pop taste tastes nice. Powder mixes nicely.”

Section Divider: Final Thoughts

Wrapping Up!

And this marks the tip of our submit on Glutamine. Thanks for studying! And as all the time, if there was one thing that wasn’t clear, one other query you may need, or if in case you have one other thought for a weblog, Electronic mail Us!

Are you on the lookout for extra to learn? Take a look at our different blogs!

Section Divider: Side Effects And Warnings

Facet Results And Warnings:

Don’t exceed really helpful every day dose. Seek the advice of a doctor prior to make use of if in case you have any medical situations. Supposed just for adults 18 years and older. Not to be used by those that are pregnant, making an attempt to change into pregnant, or nursing.

Section Divider: Disclaimer


†Please word the intention of the data offered is for reference solely. Moreover, we’re on no account offering medical recommendation or instruction. As an alternative, the data offered on this information/weblog makes use of anecdotal data and accessible research/opinions. Whereas we purpose to keep up and show correct data, we are able to’t assure it represents the newest product formulation or data. Subsequently, please go to the producer’s web site if in case you have any issues. Additionally, the data above doesn’t symbolize our views right here at Similar Day Dietary supplements. As an alternative, these are the producers’ and customers’ views and knowledge. Moreover, the Meals and Drug Administration has not evaluated these statements. Lastly, these merchandise purpose to not diagnose, deal with, remedy, or stop illness or sickness.